Twelve new genes linked with type 2 diabetes have been found in a study into the differences in people's DNA and their risk of having the condition. A consortium including Edinburgh University scientists have identified ‘important clues to the biological basis of type 2 diabetes’. It is hoped the findings will lead to better ways of treating the condition. The genes tend to be involved in working cells producing insulin, which control levels of glucose in blood. The 12 new genes brings the total number linked with type 2 diabetes to 38. The study was led by researchers at Oxford University and forms part of the Wellcome Trust case control consortium. The group of researchers, from across the UK, Europe, USA, and Canada, compared the DNA of more than 8000 people with type 2 diabetes with almost 40000 people without the condition. They then checked the genetic variations they found in another group including over 34000 people with diabetes and almost 60000 controls. Dr Jim Wilson, of Edinburgh University, said, ‘One very interesting finding is that the diabetes susceptibility genes also contain variants that increase the risk of unrelated diseases, including skin and prostate cancer, coronary heart disease, and high cholesterol.

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